Serine/threonine-protein kinase DCLK2

BE0009430ProteinHumansDCLK2

Protein kinase with a significantly reduced C(a2+)/CAM affinity and dependence compared to other members of the CaMK family. It is acted on by 1 drug in DrugBank.

Gene name
DCLK2
UniProtKB entry
Q8N568Swiss-Prot
Cellular location
Cytoplasm, cytoskeleton
Residues / weight
766 residues · 83,605 Da
Also known as
2.7.11.1 · CaMK-like CREB regulatory kinase 2 · CL2 · CLICK-II · CLICK2

Resolves to

Protein
UniProtQ8N568UniProt nameDCLK2_HUMAN
Gene
HGNCHGNC:19002NCBI Gene166614GeneCardsDCLK2
Pharmacology
IUPHAR/GtoPdb2006KEGGhsa:166614
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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4GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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9+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Serine/threonine-protein kinase DCLK2, how selective are they, and which programs against it are still in active trials?

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