Homeodomain-interacting protein kinase 3

BE0009448ProteinHumansHIPK3

Serine/threonine-protein kinase involved in transcription regulation, apoptosis and steroidogenic gene expression. It is acted on by 1 drug in DrugBank.

Gene name
HIPK3
UniProtKB entry
Q9H422Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
1,215 residues · 133,742 Da
Also known as
2.7.11.1 · Androgen receptor-interacting nuclear protein kinase · ANPK · DYRK6 · Fas-interacting serine/threonine-protein kinase

Resolves to

Protein
UniProtQ9H422UniProt nameHIPK3_HUMAN
Gene
HGNCHGNC:4915NCBI Gene10114GeneCardsHIPK3
Pharmacology
IUPHAR/GtoPdb2035KEGGhsa:10114
Structure
PDB7O7IPDB7O7J
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
Sign in
12GO termsFunction, process and component, as structured annotations
Sign in
1Pfam domainDomain architecture mapped to Pfam families and clans
Sign in
10+ReferencesStructured and connected to the statements they support
Sign in

Which approved drugs act on Homeodomain-interacting protein kinase 3, how selective are they, and which programs against it are still in active trials?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In