Leukocyte tyrosine kinase receptor

BE0009458ProteinHumansLTK

Receptor with a tyrosine-protein kinase activity (PubMed:10445845, PubMed:20548102, PubMed:30061385). It is acted on by 2 drugs in DrugBank.

Gene name
LTK
UniProtKB entry
P29376Swiss-Prot
Cellular location
Cell membrane
Residues / weight
864 residues · 91,681 Da
Also known as
2.7.10.1 · Protein tyrosine kinase 1 · TYK1

Resolves to

Protein
UniProtP29376UniProt nameLTK_HUMAN
Gene
HGNCHGNC:6721NCBI Gene4058GeneCardsLTK
Pharmacology
IUPHAR/GtoPdb1838KEGGhsa:4058
Structure
PDB7NX0PDB7NX1
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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12GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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16+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Leukocyte tyrosine kinase receptor, how selective are they, and which programs against it are still in active trials?

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