Mitogen-activated protein kinase 7

BE0009477ProteinHumansMAPK7

Plays a role in various cellular processes such as proliferation, differentiation and cell survival. It is acted on by 1 drug in DrugBank.

Gene name
MAPK7
UniProtKB entry
Q13164Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
816 residues · 88,386 Da
Also known as
2.7.11.24 · Big MAP kinase 1 · BMK-1 · BMK1 · ERK-5

Resolves to

Protein
UniProtQ13164UniProt nameMK07_HUMAN
Gene
HGNCHGNC:6880NCBI Gene5598GeneCardsMAPK7
Pharmacology
IUPHAR/GtoPdb2093KEGGhsa:5598
Structure
PDB2Q8YPDB4B99PDB4IC7
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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21GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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14+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Mitogen-activated protein kinase 7, how selective are they, and which programs against it are still in active trials?

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