MAP/microtubule affinity-regulating kinase 3

BE0009481ProteinHumansMARK3

Serine/threonine-protein kinase (PubMed:16822840, PubMed:16980613, PubMed:23666762). It is acted on by 2 drugs in DrugBank.

Gene name
MARK3
UniProtKB entry
P27448Swiss-Prot
Cellular location
Cell membrane
Residues / weight
753 residues · 84,428 Da
Also known as
2.7.11.1 · C-TAK1 · Cdc25C-associated protein kinase 1 · CTAK1 · ELKL motif kinase 2

Resolves to

Protein
UniProtP27448UniProt nameMARK3_HUMAN
Gene
HGNCHGNC:6897NCBI Gene4140GeneCardsMARK3
Pharmacology
IUPHAR/GtoPdb2099KEGGhsa:4140
Structure
PDB2QNJPDB3FE3PDB7P1L
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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8GO termsFunction, process and component, as structured annotations
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3Pfam domainsDomain architecture mapped to Pfam families and clans
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21+ReferencesStructured and connected to the statements they support
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Which approved drugs act on MAP/microtubule affinity-regulating kinase 3, how selective are they, and which programs against it are still in active trials?

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