Myosin-IIIa

BE0009495ProteinHumansMYO3A

Actin-dependent motor protein with a protein kinase activity, playing an essential role in hearing (PubMed:12032315, PubMed:29880844, PubMed:34788109). It is acted on by 1 drug in DrugBank.

Gene name
MYO3A
UniProtKB entry
Q8NEV4Swiss-Prot
Cellular location
Cytoplasm, cytoskeleton
Residues / weight
1,616 residues · 186,207 Da
Also known as
2.7.11.1

Resolves to

Protein
UniProtQ8NEV4UniProt nameMYO3A_HUMAN
Gene
HGNCHGNC:7601NCBI Gene53904GeneCardsMYO3A
Pharmacology
KEGGhsa:53904
Structure
PDB6JLE
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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16GO termsFunction, process and component, as structured annotations
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3Pfam domainsDomain architecture mapped to Pfam families and clans
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7+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Myosin-IIIa, how selective are they, and which programs against it are still in active trials?

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