Serine/threonine-protein kinase Nek9

BE0009500ProteinHumansNEK9

Pleiotropic regulator of mitotic progression, participating in the control of spindle dynamics and chromosome separation (PubMed:12101123, PubMed:12840024, PubMed:14660563, PubMed:19941817). It is acted on by 1 drug in DrugBank.

Gene name
NEK9
UniProtKB entry
Q8TD19Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
979 residues · 107,168 Da
Also known as
2.7.11.38 · KIAA1995 · NEK8 · NERCC · Nercc1 kinase

Resolves to

Protein
UniProtQ8TD19UniProt nameNEK9_HUMAN
Gene
HGNCHGNC:18591NCBI Gene91754GeneCardsNEK9
Pharmacology
KEGGhsa:91754
Structure
PDB3ZKEPDB3ZKF
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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5GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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25+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Serine/threonine-protein kinase Nek9, how selective are they, and which programs against it are still in active trials?

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