Serine/threonine-protein kinase PAK 6

BE0009509ProteinHumansPAK6

Serine/threonine protein kinase that plays a role in the regulation of gene transcription. It is acted on by 1 drug in DrugBank.

Gene name
PAK6
UniProtKB entry
Q9NQU5Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
681 residues · 74,868 Da
Also known as
2.7.11.1 · p21-activated kinase 6 · PAK-5 · PAK-6 · PAK5

Resolves to

Protein
UniProtQ9NQU5UniProt namePAK6_HUMAN
Gene
HGNCHGNC:16061NCBI Gene56924GeneCardsPAK6
Pharmacology
IUPHAR/GtoPdb2137KEGGhsa:56924
Structure
PDB2C30PDB2ODBPDB4KS7
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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6GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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12+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Serine/threonine-protein kinase PAK 6, how selective are they, and which programs against it are still in active trials?

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