Serine/threonine-protein kinase PAK 5

BE0009510ProteinHumansPAK5

Serine/threonine protein kinase that plays a role in a variety of different signaling pathways including cytoskeleton regulation, cell migration, proliferation or cell survival. It is acted on by 1 drug in DrugBank.

Gene name
PAK5
UniProtKB entry
Q9P286Swiss-Prot
Cellular location
Mitochondrion
Residues / weight
719 residues · 80,744 Da
Also known as
2.7.11.1 · KIAA1264 · p21-activated kinase 5 · p21-activated kinase 7 · PAK-5

Resolves to

Protein
UniProtQ9P286UniProt namePAK5_HUMAN
Gene
HGNCHGNC:15916NCBI Gene57144GeneCardsPAK5
Pharmacology
IUPHAR/GtoPdb2138KEGGhsa:57144
Structure
PDB2F57PDB8C12
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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8GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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15+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Serine/threonine-protein kinase PAK 5, how selective are they, and which programs against it are still in active trials?

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