Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma

BE0009518ProteinHumansPIP4K2C

Phosphatidylinositol 5-phosphate 4-kinase with low enzymatic activity. It is acted on by 1 drug in DrugBank.

Gene name
PIP4K2C
UniProtKB entry
Q8TBX8Swiss-Prot
Cellular location
Endoplasmic reticulum
Residues / weight
421 residues · 47,300 Da
Also known as
2.7.1.149 · Phosphatidylinositol 5-phosphate 4-kinase type II gamma · PI(5)P 4-kinase type II gamma · PIP4KII-gamma · PIP5K2C

Resolves to

Protein
UniProtQ8TBX8UniProt namePI42C_HUMAN
Gene
HGNCHGNC:23786NCBI Gene79837GeneCardsPIP4K2C
Pharmacology
IUPHAR/GtoPdb2163KEGGhsa:79837
Structure
PDB2GK9PDB7QIEPDB7QPN
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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7GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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7+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma, how selective are they, and which programs against it are still in active trials?

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