Serine/threonine-protein kinase N2

BE0009521ProteinHumansPKN2

PKC-related serine/threonine-protein kinase and Rho/Rac effector protein that participates in specific signal transduction responses in the cell. It is acted on by 1 drug in DrugBank.

Gene name
PKN2
UniProtKB entry
Q16513Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
984 residues · 112,034 Da
Also known as
2.7.11.13 · PKN gamma · PRK2 · PRKCL2 · Protein kinase C-like 2

Resolves to

Protein
UniProtQ16513UniProt namePKN2_HUMAN
Gene
HGNCHGNC:9406NCBI Gene5586GeneCardsPKN2
Pharmacology
IUPHAR/GtoPdb1521KEGGhsa:5586
Structure
PDB4CRSPDB4RRVPDB6CCY
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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3GO termsFunction, process and component, as structured annotations
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3Pfam domainsDomain architecture mapped to Pfam families and clans
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36+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Serine/threonine-protein kinase N2, how selective are they, and which programs against it are still in active trials?

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