Polyamine deacetylase HDAC10

BE0009579ProteinHumansHDAC10

Polyamine deacetylase (PDAC), which acts preferentially on N(8)-acetylspermidine, and also on acetylcadaverine and acetylputrescine (PubMed:28516954). It is acted on by 2 drugs in DrugBank.

Gene name
HDAC10
UniProtKB entry
Q969S8Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
669 residues · 71,444 Da
Also known as
3.5.1.48 · 3.5.1.62 · HD10 · Histone deacetylase 10

Resolves to

Protein
UniProtQ969S8UniProt nameHDA10_HUMAN
Gene
HGNCHGNC:18128NCBI Gene83933GeneCardsHDAC10
Pharmacology
IUPHAR/GtoPdb2614KEGGhsa:83933
Drugs

What you can answer from here — as of September 03, 2024

2DrugsApproved to experimental, with action, bond type and pharmacological action
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1Clinical trialTrials of drugs acting on it, by phase and status
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13GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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14+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Polyamine deacetylase HDAC10, how selective are they, and which programs against it are still in active trials?

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