5-hydroxytryptamine receptor 3C

BE0009584ProteinHumansHTR3C

Forms serotonin (5-hydroxytryptamine/5-HT3)-activated cation-selective channel complexes, which when activated cause fast, depolarizing responses in neurons. It is acted on by 1 drug in DrugBank.

Gene name
HTR3C
UniProtKB entry
Q8WXA8Swiss-Prot
Cellular location
Postsynaptic cell membrane
Residues / weight
447 residues · 50,219 Da
Also known as
5-HT3-C · 5-HT3C · Serotonin receptor 3C

Resolves to

Protein
UniProtQ8WXA8UniProt name5HT3C_HUMAN
Gene
HGNCHGNC:24003NCBI Gene170572GeneCardsHTR3C
Pharmacology
KEGGhsa:170572
Drugs

What you can answer from here — as of August 08, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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5GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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5+ReferencesStructured and connected to the statements they support
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Which approved drugs act on 5-hydroxytryptamine receptor 3C, how selective are they, and which programs against it are still in active trials?

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