5-hydroxytryptamine receptor 3E

BE0009586ProteinHumansHTR3E

Forms serotonin (5-hydroxytryptamine/5-HT3)-activated cation-selective channel complexes, which when activated cause fast, depolarizing responses in neurons. It is acted on by 1 drug in DrugBank.

Gene name
HTR3E
UniProtKB entry
A5X5Y0Swiss-Prot
Cellular location
Postsynaptic cell membrane
Residues / weight
456 residues · 51,437 Da
Also known as
5-HT3-E · 5-HT3E · Serotonin receptor 3E

Resolves to

Protein
UniProtA5X5Y0UniProt name5HT3E_HUMAN
Gene
HGNCHGNC:24005NCBI Gene285242GeneCardsHTR3E
Pharmacology
KEGGhsa:285242
Drugs

What you can answer from here — as of August 08, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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5GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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7+ReferencesStructured and connected to the statements they support
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Which approved drugs act on 5-hydroxytryptamine receptor 3E, how selective are they, and which programs against it are still in active trials?

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