Histone deacetylase 11

BE0009610ProteinHumansHDAC11

Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). It is acted on by 1 drug in DrugBank.

Gene name
HDAC11
UniProtKB entry
Q96DB2Swiss-Prot
Cellular location
Nucleus
Residues / weight
347 residues · 39,183 Da
Also known as
3.5.1.98 · HD11

Resolves to

Protein
UniProtQ96DB2UniProt nameHDA11_HUMAN
Gene
HGNCHGNC:19086NCBI Gene79885GeneCardsHDAC11
Pharmacology
IUPHAR/GtoPdb2615KEGGhsa:79885
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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2Clinical trialsTrials of drugs acting on it, by phase and status
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5GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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9+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Histone deacetylase 11, and which indications are they being tested in?

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