Phospholipid transfer protein

BE0009656ProteinHumansPLTP

Mediates the transfer of phospholipids and free cholesterol from triglyceride-rich lipoproteins (low density lipoproteins or LDL and very low density lipoproteins or VLDL) into high-density lipoproteins (HDL) as well as the exchange of phospholipids between... It is acted on by 2 drugs in DrugBank.

Gene name
PLTP
UniProtKB entry
P55058Swiss-Prot
Cellular location
Secreted
Residues / weight
493 residues · 54,739 Da
Also known as
Lipid transfer protein II

Resolves to

Protein
UniProtP55058UniProt namePLTP_HUMAN
Gene
HGNCHGNC:9093NCBI Gene5360GeneCardsPLTP
Pharmacology
KEGGhsa:5360
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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14GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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15+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Phospholipid transfer protein, how selective are they, and which programs against it are still in active trials?

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