Phosphodiesterase isozyme 4
Details
- Name
- Phosphodiesterase isozyme 4
- Kind
- protein
- Synonyms
- Not Available
- Gene Name
- PDE4
- UniProtKB Entry
- Q86V67TrEMBL
- Organism
- Humans
- NCBI Taxonomy ID
- 9606
- Amino acid sequence
>lcl|BSEQ0052056|Phosphodiesterase isozyme 4 MVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLSNPTKPLELYRQWTDRIMAEFFQQGD RERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADL
- Number of residues
- 102
- Molecular Weight
- 11946.535
- Theoretical pI
- Not Available
- GO Classification
- Functions3',5'-cyclic-nucleotide phosphodiesterase activityProcessessignal transduction
- General Function
- Not Available
- Specific Function
- 3',5'-cyclic-AMP phosphodiesterase activity
- Pfam Domain Function
- PDEase_I (PF00233)
- Signal Regions
- Not Available
- Transmembrane Regions
- Not Available
- Cellular Location
- Not Available
- Gene sequence
- Not Available
- Chromosome Location
- Not Available
- Locus
- Not Available
- External Identifiers
Resource Link UniProtKB ID Q86V67 UniProtKB Entry Name Q86V67_HUMAN - General References
- Zhou L, Thompson WJ, Potter DE: Multiple cyclic nucleotide phosphodiesterases in human trabecular meshwork cells. Invest Ophthalmol Vis Sci. 1999 Jul;40(8):1745-52. [Article]
Associated Data
- Drug Relations
Drug Drug group Pharmacological action? Type Actions Details Apremilast approved, investigational yes target inhibitor Details