Phosphodiesterase isozyme 4

Details

Name
Phosphodiesterase isozyme 4
Kind
protein
Synonyms
Not Available
Gene Name
PDE4
UniProtKB Entry
Q86V67TrEMBL
Organism
Humans
NCBI Taxonomy ID
9606
Amino acid sequence
>lcl|BSEQ0052056|Phosphodiesterase isozyme 4
MVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLSNPTKPLELYRQWTDRIMAEFFQQGD
RERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADL
Number of residues
102
Molecular Weight
11946.535
Theoretical pI
Not Available
GO Classification
Functions
3',5'-cyclic-nucleotide phosphodiesterase activity
Processes
signal transduction
General Function
Not Available
Specific Function
3',5'-cyclic-AMP phosphodiesterase activity
Pfam Domain Function
Signal Regions
Not Available
Transmembrane Regions
Not Available
Cellular Location
Not Available
Gene sequence
Not Available
Chromosome Location
Not Available
Locus
Not Available
External Identifiers
ResourceLink
UniProtKB IDQ86V67
UniProtKB Entry NameQ86V67_HUMAN
General References
  1. Zhou L, Thompson WJ, Potter DE: Multiple cyclic nucleotide phosphodiesterases in human trabecular meshwork cells. Invest Ophthalmol Vis Sci. 1999 Jul;40(8):1745-52. [Article]

Associated Data

Drug Relations
DrugDrug groupPharmacological action?TypeActionsDetails
Apremilastapproved, investigationalyestargetinhibitorDetails