UK-500001

DB12837InvestigationalSmall molecule

UK-500,001 has been used in trials studying the treatment of Pulmonary Disease, Chronic Obstructive.

Mechanism: Pharmacologically active on Phosphodiesterase isozyme 4
Curator reviewed
Formula / weight: C₂₆H₂₄F₃N₃O₄ · 499.49 g/mol (avg)
Code names: UK-500001

Resolves to

Compound

Structure

InChIKeyOHIUQAZROSYCMC-CALCHBBNSA-NSMILESCC1=CC(C(=O)N[C@H]2CC[C@H](CC2)NC(=O)C2=C(OC3=CC(F)=C(F)C=C3)N=CC(F)=C2)=C(O)C=C1

Targets

What you can answer from here — as of June 15, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

2+ReferencesStructured and connected to the statements they support

Which drugs share a target with UK-500001, and which of those have an active Phase 3 trial?

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