Sulfotransferase 1C2

BE0009763ProteinHumansSULT1C2

Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) to catalyze the sulfate conjugation of phenolic compounds (PubMed:10481272, PubMed:10783263, PubMed:9852044). It is acted on by 1 drug in DrugBank.

Gene name
SULT1C2
UniProtKB entry
O00338Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
296 residues · 34,880 Da
Also known as
2.8.2.1 · humSULTC2 · ST1C2 · Sulfotransferase 1C1 · SULT1C#1

Resolves to

Protein
UniProtO00338UniProt nameST1C2_HUMAN
Gene
HGNCHGNC:11456NCBI Gene6819GeneCardsSULT1C2
Pharmacology
KEGGhsa:6819
Structure
PDB3BFX
Drugs

What you can answer from here — as of September 25, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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2GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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10+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Sulfotransferase 1C2, how selective are they, and which programs against it are still in active trials?

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