Dystrophin

BE0009794ProteinHumansDMD

Anchors the extracellular matrix to the cytoskeleton via F-actin. It is acted on by 4 drugs in DrugBank.

Gene name
DMD
UniProtKB entry
P11532Swiss-Prot
Cellular location
Cell membrane, sarcolemma
Residues / weight
3,685 residues · 426,775 Da

Resolves to

Protein
UniProtP11532UniProt nameDMD_HUMAN
Gene
HGNCHGNC:2928NCBI Gene1756GeneCardsDMD
Pharmacology
KEGGhsa:1756
Structure
PDB1DXXPDB1EG3PDB1EG4
Drugs

What you can answer from here — as of December 17, 2019

4DrugsApproved to experimental, with action, bond type and pharmacological action
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6Clinical trialsTrials of drugs acting on it, by phase and status
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32GO termsFunction, process and component, as structured annotations
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6Pfam domainsDomain architecture mapped to Pfam families and clans
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57+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Dystrophin, how selective are they, and which programs against it are still in active trials?

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