Renadirsen

DB19132InvestigationalSmall molecule

Renadirsen is under investigation in clinical trial NCT04433234 (Long-term, Extension Study of Ds-5141b in Patients With Duchenne Muscular Dystrophy).

Mechanism: Pharmacologically active on Dystrophin
Curator reviewed
Formula / weight: C₂₀₈H₂₇₅N₆₃O₁₁₀P₁₈S₁₈ · 6552.43 g/mol (avg)
Also known as: Renapersen
Code names: DS-5141b

Resolves to

Compound

UNII4RW6WRD7SWCAS1782108-31-9

Structure

InChIKeyDYDGGTWPZKPVKH-UHFFFAOYSA-NSMILES

CO[C@@H]1[C@H](OP(S)(=O)OC[C@H]2O[C@H]([C@H](OC)[C@@H]2OP(S)(=O)OC[C@@]23CCO[C@@H]([C@@H](O2)N2C=C(C)C(=O)NC2=O)[C@@H]3OP(S)(=O)OC[C@H]2O[C@H]([C@H](OC)[C@@H]2OP(S)(=O)OC[C@@]23CCO[C@@H]([C@@H](O2)N2C=C(C)C(N)=NC2=O)[C@@H]3OP(S)(=O)OC[C@@]23CCO[C@@H]([C@@H](O2)N2C=C(C)C(N)=NC2=O)[C@@H]3OP(S)(=O)OC[C@H]2O[C@H]([C@H](OC)[C@@H]2OP(S)(=O)OC[C@H]2O[C@H]([C@H](OC)[C@@H]2OP(S)(=O)OC[C@@]23CCO[C@@H]([C@@H](O2)N2C=C(C)C(N)=NC2=O)[C@@H]3OP(S)(=O)OC[C@@]23CCO[C@@H]([C@@H](O2)N2C=C(C)C(N)=NC2=O)[C@@H]3OP(S)(=O)OCCO)N2C=CC(=O)NC2=O)N2C=NC3=C(N)N=CN=C23)N2C=NC3=C2N=C(N)NC3=O)N2C=NC3=C(N)N=CN=C23)[C@@H](COP(S)(=O)O[C@H]2[C@H]3OCC[C@]2(COP(S)(=O)O[C@H]2[C@H]4OCC[C@]2(COP(S)(=O)O[C@@H]2[C@@H](COP(S)(=O)O[C@@H]5[C@@H](COP(S)(=O)O[C@H]6[C@H]7OCC[C@]6(COP(S)(=O)O[C@H]6[C@H]8OCC[C@]6(COP(S)(=O)O[C@@H]6[C@@H](COP(S)(=O)O[C@H]9[C@H]%10OCC[C@]9(CO)O[C@H]%10N9C=C(C)C(N)=NC9=O)O[C@H]([C@@H]6OC)N6C=NC9=C6N=C(N)NC9=O)O[C@H]8N6C=C(C)C(N)=NC6=O)O[C@H]7N6C=C(C)C(=O)NC6=O)O[C@H]([C@@H]5OC)N5C=NC6=C5N=C(N)NC6=O)O[C@H]([C@@H]2OC)N2C=CC(N)=NC2=O)O[C@H]4N2C=C(C)C(N)=NC2=O)O[C@H]3N2C=C(C)C(N)=NC2=O)O[C@H]1N1C=NC2=C(N)N=CN=C12

Targets

P11532DMD

What you can answer from here — as of October 07, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

2Clinical trialsPhase, status and sponsor resolved per trial

3+ReferencesStructured and connected to the statements they support

Which drugs share a target with Renadirsen, and which of those have an active Phase 3 trial?

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