P2X purinoceptor 3

BE0009818ProteinHumansP2RX3

Extracellular ATP-activated non-selective cation channel (PubMed:10440098, PubMed:27626375, PubMed:29674445, PubMed:31232692). It is acted on by 6 drugs in DrugBank.

Gene name
P2RX3
UniProtKB entry
P56373Swiss-Prot
Cellular location
Cell membrane
Residues / weight
397 residues · 44,289 Da
Also known as
ATP receptor · P2X3 · Purinergic receptor

Resolves to

Protein
UniProtP56373UniProt nameP2RX3_HUMAN
Gene
HGNCHGNC:8534NCBI Gene5024GeneCardsP2RX3
Pharmacology
IUPHAR/GtoPdb480KEGGhsa:5024
Structure
PDB21DXPDB21FGPDB5SVJ
Drugs

What you can answer from here — as of January 22, 2020

6DrugsApproved to experimental, with action, bond type and pharmacological action
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2Clinical trialsTrials of drugs acting on it, by phase and status
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7GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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26+ReferencesStructured and connected to the statements they support
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Which approved drugs act on P2X purinoceptor 3, how selective are they, and which programs against it are still in active trials?

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