Filapixant

DB21467ExperimentalSmall molecule

Filapixant is a small molecule drug. The usage of the INN stem '-pixant' in the name indicates that Filapixant is a purinoreceptor (P2X) antagonist. Filapixant has a monoisotopic molecular weight...

Mechanism: Pharmacologically active on P2X purinoceptor 3
Curator reviewed
Formula / weight: C₂₄H₂₆F₃N₅O₃S · 521.56 g/mol (avg)

Resolves to

Compound

UNIIB35HB63WZFCAS1948232-63-0ChEMBLCHEMBL5802745

Structure

InChIKeyMROBUJILSMBILX-FOIQADDNSA-NSMILESC[C@@H](NC(=O)C1=CC(=CC(OC[C@H]2CN(C)CCO2)=C1)C1=NC=C(C)S1)C1=CN=C(N=C1)C(F)(F)F

Targets

P56373P2RX3

What you can answer from here — as of August 31, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

6+ReferencesStructured and connected to the statements they support

Which drugs share a target with Filapixant, and which of those have an active Phase 3 trial?

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