Outer membrane porin C

BE0009852ProteinEscherichia coli (strain K12)ompC

Forms pores that allow passive diffusion of small molecules across the outer membrane. It is acted on by 1 drug in DrugBank.

Gene name
ompC
UniProtKB entry
P06996Swiss-Prot
Cellular location
Cell outer membrane
Residues / weight
367 residues · 40,368 Da
Also known as
meoA · Outer membrane protein 1B · Outer membrane protein C · par · Porin OmpC

Resolves to

Protein
UniProtP06996UniProt nameOMPC_ECOLI
Gene
NCBI Gene946716
Pharmacology
KEGGecj:JW2203
Structure
PDB2J1NPDB2J4UPDB2ZLE
Drugs

What you can answer from here — as of February 11, 2020

1DrugApproved to experimental, with action, bond type and pharmacological action
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8GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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13+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Outer membrane porin C, how selective are they, and which programs against it are still in active trials?

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