Zinc transporter 7

BE0009885ProteinHumansSLC30A7

Zinc ion transporter mediating zinc entry from the cytosol into the lumen of organelles along the secretory pathway (PubMed:15525635, PubMed:15994300). It is acted on by 2 drugs in DrugBank.

Gene name
SLC30A7
UniProtKB entry
Q8NEW0Swiss-Prot
Cellular location
Golgi apparatus membrane
Residues / weight
376 residues · 41,626 Da
Also known as
Solute carrier family 30 member 7 · ZnT-7 · Znt-like transporter 2 · ZNT7 · ZNTL2

Resolves to

Protein
UniProtQ8NEW0UniProt nameZNT7_HUMAN
Gene
HGNCHGNC:19306NCBI Gene148867GeneCardsSLC30A7
Pharmacology
KEGGhsa:148867
Structure
PDB8J7TPDB8J7UPDB8J7V
Drugs

What you can answer from here — as of April 13, 2020

2DrugsApproved to experimental, with action, bond type and pharmacological action
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11GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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9+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Zinc transporter 7, how selective are they, and which programs against it are still in active trials?

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