Zinc transporter ZIP6

BE0009887ProteinHumansSLC39A6

Zinc-influx transporter which plays a role in zinc homeostasis and in the induction of epithelial-to-mesenchymal transition (EMT) (PubMed:12839489, PubMed:18272141, PubMed:21422171, PubMed:23919497, PubMed:27274087, PubMed:34394081). It is acted on by 3 drugs in DrugBank.

Gene name
SLC39A6
UniProtKB entry
Q13433Swiss-Prot
Cellular location
Cell membrane
Residues / weight
755 residues · 85,046 Da
Also known as
Estrogen-regulated protein LIV-1 · LIV1 · Solute carrier family 39 member 6 · ZIP-6 · ZIP6

Resolves to

Protein
UniProtQ13433UniProt nameS39A6_HUMAN
Gene
HGNCHGNC:18607NCBI Gene25800GeneCardsSLC39A6
Pharmacology
KEGGhsa:25800
Drugs

What you can answer from here — as of April 13, 2020

3DrugsApproved to experimental, with action, bond type and pharmacological action
Sign in
8GO termsFunction, process and component, as structured annotations
Sign in
1Pfam domainDomain architecture mapped to Pfam families and clans
Sign in
14+ReferencesStructured and connected to the statements they support
Sign in

Which approved drugs act on Zinc transporter ZIP6, how selective are they, and which programs against it are still in active trials?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In