Zinc transporter ZIP12

BE0009897ProteinHumansSLC39A12

Uniporter that promotes Zn(2+) import from the extracellular space to the cytoplasm across the cell membrane. It is acted on by 2 drugs in DrugBank.

Gene name
SLC39A12
UniProtKB entry
Q504Y0Swiss-Prot
Cellular location
Membrane
Residues / weight
691 residues · 76,665 Da
Also known as
LIV-1 subfamily of ZIP zinc transporter 8 · LZT-Hs8 · Solute carrier family 39 member 12 · ZIP-12 · ZIP12

Resolves to

Protein
UniProtQ504Y0UniProt nameS39AC_HUMAN
Gene
HGNCHGNC:20860NCBI Gene221074GeneCardsSLC39A12
Pharmacology
KEGGhsa:221074
Drugs

What you can answer from here — as of April 13, 2020

2DrugsApproved to experimental, with action, bond type and pharmacological action
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6GO termsFunction, process and component, as structured annotations
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3Pfam domainsDomain architecture mapped to Pfam families and clans
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9+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Zinc transporter ZIP12, how selective are they, and which programs against it are still in active trials?

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