Zinc transporter ZIP11

BE0009906ProteinHumansSLC39A11

Zinc importer that regulates cytosolic zinc concentrations either via zinc influx from the extracellular compartment or efflux from intracellular organelles such as Golgi apparatus. It is acted on by 2 drugs in DrugBank.

Gene name
SLC39A11
UniProtKB entry
Q8N1S5Swiss-Prot
Cellular location
Cell membrane
Residues / weight
342 residues · 35,396 Da
Also known as
C17orf26 · Solute carrier family 39 member 11 · ZIP-11 · ZIP11 · Zrt- and Irt-like protein 11

Resolves to

Protein
UniProtQ8N1S5UniProt nameS39AB_HUMAN
Gene
HGNCHGNC:14463NCBI Gene201266GeneCardsSLC39A11
Pharmacology
KEGGhsa:201266
Drugs

What you can answer from here — as of April 13, 2020

2DrugsApproved to experimental, with action, bond type and pharmacological action
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2GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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6+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Zinc transporter ZIP11, how selective are they, and which programs against it are still in active trials?

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