Haptoglobin

BE0009911ProteinHumansHP

As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. It is acted on by 3 drugs in DrugBank.

Gene name
HP
UniProtKB entry
P00738Swiss-Prot
Cellular location
Secreted
Residues / weight
406 residues · 45,205 Da
Also known as
Zonulin

Resolves to

Protein
UniProtP00738UniProt nameHPT_HUMAN
Gene
HGNCHGNC:5141NCBI Gene3240GeneCardsHP
Pharmacology
KEGGhsa:3240
Structure
PDB4WJGPDB4X0LPDB5HU6
Drugs

What you can answer from here — as of April 15, 2020

3DrugsApproved to experimental, with action, bond type and pharmacological action
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8Clinical trialsTrials of drugs acting on it, by phase and status
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1Pfam domainDomain architecture mapped to Pfam families and clans
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34+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Haptoglobin, how selective are they, and which programs against it are still in active trials?

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