Beta-galactosidase

BE0009999ProteinHumansGLB1

Cleaves beta-linked terminal galactosyl residues from gangliosides, glycoproteins, and glycosaminoglycans. It is acted on by 2 drugs in DrugBank.

Gene name
GLB1
UniProtKB entry
P16278Swiss-Prot
Cellular location
Lysosome
Residues / weight
677 residues · 76,074 Da
Also known as
3.2.1.23 · Acid beta-galactosidase · Elastin receptor 1 · ELNR1 · Lactase

Resolves to

Protein
UniProtP16278UniProt nameBGAL_HUMAN
Gene
HGNCHGNC:4298NCBI Gene2720GeneCardsGLB1
Pharmacology
KEGGhsa:2720
Structure
PDB3THCPDB3THDPDB3WEZ
Drugs

What you can answer from here — as of May 26, 2020

2DrugsApproved to experimental, with action, bond type and pharmacological action
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2Clinical trialsTrials of drugs acting on it, by phase and status
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15GO termsFunction, process and component, as structured annotations
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3Pfam domainsDomain architecture mapped to Pfam families and clans
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47+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Beta-galactosidase, how selective are they, and which programs against it are still in active trials?

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