Equilibrative nucleoside transporter 3

BE0010035ProteinHumansSLC29A3

Uniporter that mediates the facilitative transport of nucleoside across lysosomal and mitochondrial membranes (PubMed:15701636, PubMed:19164483, PubMed:20595384, PubMed:28729424). It is acted on by 1 drug in DrugBank.

Gene name
SLC29A3
UniProtKB entry
Q9BZD2Swiss-Prot
Cellular location
Lysosome membrane
Residues / weight
475 residues · 51,814 Da
Also known as
ENT3 · hENT3 · Solute carrier family 29 member 3

Resolves to

Pharmacology

What you can answer from here — as of February 24, 2021

1DrugApproved to experimental, with action, bond type and pharmacological action
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5GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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19+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Equilibrative nucleoside transporter 3, how selective are they, and which programs against it are still in active trials?

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