UbiA prenyltransferase domain-containing protein 1

BE0010058ProteinHumansUBIAD1

Prenyltransferase that mediates the formation of menaquinone-4 (MK-4) and coenzyme Q10 (PubMed:20953171, PubMed:23374346). It is acted on by 1 drug in DrugBank.

Gene name
UBIAD1
UniProtKB entry
Q9Y5Z9Swiss-Prot
Cellular location
Endoplasmic reticulum membrane
Residues / weight
338 residues · 36,831 Da
Also known as
2.5.1.- · 2.5.1.39 · TERE1 · Transitional epithelial response protein 1

Resolves to

Protein
UniProtQ9Y5Z9UniProt nameUBIA1_HUMAN
Gene
HGNCHGNC:30791NCBI Gene29914GeneCardsUBIAD1
Pharmacology
KEGGhsa:29914
Drugs

What you can answer from here — as of April 26, 2021

1DrugApproved to experimental, with action, bond type and pharmacological action
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1Metabolic reactionDrug transformations it catalyses, substrate to product
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3GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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19+ReferencesStructured and connected to the statements they support
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Which approved drugs act on UbiA prenyltransferase domain-containing protein 1, how selective are they, and which programs against it are still in active trials?

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