GTP-binding protein RHO1

BE0010067ProteinBaker's yeastRHO1

Acts as a central regulator in the cell wall integrity signaling pathway, which is regulated by the cell cycle and in response to various types of cell wall stress. It is acted on by 1 drug in DrugBank.

Gene name
RHO1
UniProtKB entry
P06780Swiss-Prot
Cellular location
Cell membrane
Residues / weight
209 residues · 23,152 Da
Also known as
3.6.5.2 · Rho-type GTPase 1

Resolves to

Protein
UniProtP06780UniProt nameRHO1_YEAST
Gene
NCBI Gene856294
Pharmacology
KEGGsce:YPR165W
Structure
PDB3A58
Drugs

What you can answer from here — as of June 03, 2021

1DrugApproved to experimental, with action, bond type and pharmacological action
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45GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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33+ReferencesStructured and connected to the statements they support
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Which approved drugs act on GTP-binding protein RHO1, how selective are they, and which programs against it are still in active trials?

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