Free fatty acid receptor 2

BE0010131ProteinHumansFFAR2

G protein-coupled receptor that is activated by a major product of dietary fiber digestion, the short chain fatty acids (SCFAs), and that plays a role in the regulation of whole-body energy homeostasis and in intestinal... It is acted on by 4 drugs in DrugBank.

Gene name
FFAR2
UniProtKB entry
O15552Swiss-Prot
Cellular location
Cell membrane
Residues / weight
330 residues · 37,143 Da
Also known as
FFA2 · G protein-coupled receptor 43 · GPCR43 · GPR43

Resolves to

Protein
UniProtO15552UniProt nameFFAR2_HUMAN
Gene
HGNCHGNC:4501NCBI Gene2867GeneCardsFFAR2
Pharmacology
IUPHAR/GtoPdb226KEGGhsa:2867
Structure
PDB8J22PDB8J23PDB8J24
Drugs

What you can answer from here — as of November 10, 2021

4DrugsApproved to experimental, with action, bond type and pharmacological action
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16GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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23+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Free fatty acid receptor 2, and which indications are they being tested in?

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