Propionate ion

DB19384InvestigationalSmall molecule

Propionate ion is under investigation in clinical trial NCT00846326 (Preventing Tolerance to Oxymetazoline in Allergic Rhinitis).

Mechanism: Pharmacologically active on Histone deacetylase, Free fatty acid receptor 2, and Free fatty acid receptor 3
Curator reviewed
Formula / weight: C₃H₅O₂ · 73.072 g/mol (avg)
Also known as: Propanoate ion · Propanoic acid anion · Propanoic acid, ion(1-) · Propionate

Resolves to

Compound

UNIIAKW5EM890CCAS72-03-7ChEBI17272PubChem104745

Clinical / RWD

RxNorm121047

Structure

InChIKeyXBDQKXXYIPTUBI-UHFFFAOYSA-MSMILESCCC([O-])=O

Targets

O15552FFAR2O14843FFAR3

Transporters

P53985SLC16A1Q8N695SLC5A8

What you can answer from here — as of September 23, 2026

3Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

2TransportersSubstrate / inhibitor direction, not just membership

Listed above

25Clinical trialsPhase, status and sponsor resolved per trial

8+ReferencesStructured and connected to the statements they support

Which drugs share a target with Propionate ion, and which of those have an active Phase 3 trial?

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