Inhibin beta A chain

BE0010139ProteinHumansINHBA

Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development... It is acted on by 2 drugs in DrugBank.

Gene name
INHBA
UniProtKB entry
P08476Swiss-Prot
Cellular location
Secreted
Residues / weight
426 residues · 47,442 Da
Also known as
Activin beta-A chain · EDF · Erythroid differentiation protein

Resolves to

Protein
UniProtP08476UniProt nameINHBA_HUMAN
Gene
HGNCHGNC:6066NCBI Gene3624GeneCardsINHBA
Pharmacology
KEGGhsa:3624
Structure
PDB1NYSPDB1NYUPDB1S4Y
Drugs

What you can answer from here — as of November 23, 2021

2DrugsApproved to experimental, with action, bond type and pharmacological action
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18GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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18+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Inhibin beta A chain, how selective are they, and which programs against it are still in active trials?

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