7beta-hydroxysteroid dehydrogenase

BE0010212ProteinRuminococcus gnavus ATCC 29149

7beta-hydroxysteroid dehydrogenase that catalyzes the reduction of the 7-oxo group of 7-oxo-lithocholate (7-oxo-LCA), to yield ursodeoxycholate (UDCA). It is acted on by 1 drug in DrugBank.

UniProtKB entry
A7B4V1Swiss-Prot
Residues / weight
263 residues · 29,289 Da
Also known as
1.1.1.201 · 7beta-HSDH · NADP-dependent 7beta-hydroxysteroid dehydrogenase

Resolves to

Protein
UniProtA7B4V1UniProt nameHSDHB_MEDG7
Gene
NCBI Gene57433518
Drugs

What you can answer from here — as of January 27, 2023

1DrugApproved to experimental, with action, bond type and pharmacological action
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5GO termsFunction, process and component, as structured annotations
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2+ReferencesStructured and connected to the statements they support
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Which compounds in development act on 7beta-hydroxysteroid dehydrogenase, and which indications are they being tested in?

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