L-selectin

BE0010361ProteinHumansSELL

Calcium-dependent lectin that mediates cell adhesion by binding to glycoproteins on neighboring cells (PubMed:12403782, PubMed:28011641, PubMed:28489325). It is acted on by 4 drugs in DrugBank.

Gene name
SELL
UniProtKB entry
P14151Swiss-Prot
Cellular location
Cell membrane
Residues / weight
372 residues · 42,187 Da
Also known as
CD62 antigen-like family member L · gp90-MEL · LAM-1 · LECAM1 · Leukocyte adhesion molecule 1

Resolves to

Protein
UniProtP14151UniProt nameLYAM1_HUMAN
Gene
HGNCHGNC:10720NCBI Gene6402GeneCardsSELL
Pharmacology
KEGGhsa:6402
Structure
PDB2LGFPDB3CFWPDB5VC1
Drugs

What you can answer from here — as of October 31, 2023

4DrugsApproved to experimental, with action, bond type and pharmacological action
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6Clinical trialsTrials of drugs acting on it, by phase and status
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3GO termsFunction, process and component, as structured annotations
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3Pfam domainsDomain architecture mapped to Pfam families and clans
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6+ReferencesStructured and connected to the statements they support
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Which compounds in development act on L-selectin, and which indications are they being tested in?

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