Tumor necrosis factor ligand superfamily member 13

BE0010394ProteinHumansTNFSF13

Cytokine that binds to TNFRSF13B/TACI and to TNFRSF17/BCMA. It is acted on by 5 drugs in DrugBank.

Gene name
TNFSF13
UniProtKB entry
O75888Swiss-Prot
Cellular location
Secreted
Residues / weight
250 residues · 27,433 Da
Also known as
A proliferation-inducing ligand · APRIL · TALL-2 · TALL2 · TNF- and APOL-related leukocyte expressed ligand 2

Resolves to

Protein
UniProtO75888UniProt nameTNF13_HUMAN
Gene
HGNCHGNC:11928NCBI Gene8741GeneCardsTNFSF13
Pharmacology
KEGGhsa:8741
Structure
PDB4ZCH
Drugs

What you can answer from here — as of October 31, 2023

5DrugsApproved to experimental, with action, bond type and pharmacological action
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3Clinical trialsTrials of drugs acting on it, by phase and status
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14GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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12+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Tumor necrosis factor ligand superfamily member 13, how selective are they, and which programs against it are still in active trials?

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