Friend leukemia integration 1 transcription factor

BE0010454ProteinHumansFLI1

Sequence-specific transcriptional activator (PubMed:24100448, PubMed:26316623, PubMed:28255014). It is acted on by 1 drug in DrugBank.

Gene name
FLI1
UniProtKB entry
Q01543Swiss-Prot
Cellular location
Nucleus
Residues / weight
452 residues · 50,982 Da
Also known as
Proto-oncogene Fli-1 · Transcription factor ERGB

Resolves to

Protein
UniProtQ01543UniProt nameFLI1_HUMAN
Gene
HGNCHGNC:3749NCBI Gene2313GeneCardsFLI1
Pharmacology
KEGGhsa:2313
Structure
PDB1FLIPDB1X66PDB2YTU
Drugs

What you can answer from here — as of October 31, 2023

1DrugApproved to experimental, with action, bond type and pharmacological action
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3Clinical trialsTrials of drugs acting on it, by phase and status
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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5+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Friend leukemia integration 1 transcription factor, and which indications are they being tested in?

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