RNA-binding protein EWS

BE0010458ProteinHumansEWSR1

Binds to ssRNA containing the consensus sequence 5'-AGGUAA-3' (PubMed:21256132). It is acted on by 1 drug in DrugBank.

Gene name
EWSR1
UniProtKB entry
Q01844Swiss-Prot
Cellular location
Nucleus
Residues / weight
656 residues · 68,478 Da
Also known as
Ewing sarcoma breakpoint region 1 protein · EWS · EWS oncogene

Resolves to

Protein
UniProtQ01844UniProt nameEWS_HUMAN
Gene
HGNCHGNC:3508NCBI Gene2130GeneCardsEWSR1
Pharmacology
KEGGhsa:2130
Structure
PDB2CPE
Drugs

What you can answer from here — as of October 31, 2023

1DrugApproved to experimental, with action, bond type and pharmacological action
Sign in
5Clinical trialsTrials of drugs acting on it, by phase and status
Sign in
1GO termFunction, process and component, as structured annotations
Sign in
2Pfam domainsDomain architecture mapped to Pfam families and clans
Sign in
2+ReferencesStructured and connected to the statements they support
Sign in

Which compounds in development act on RNA-binding protein EWS, and which indications are they being tested in?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In