Dual specificity protein phosphatase 5

BE0010466ProteinHumansDUSP5

Dual specificity protein phosphatase; active with phosphotyrosine, phosphoserine and phosphothreonine residues. It is acted on by 1 drug in DrugBank.

Gene name
DUSP5
UniProtKB entry
Q16690Swiss-Prot
Cellular location
Nucleus
Residues / weight
384 residues · 42,047 Da
Also known as
3.1.3.16 · 3.1.3.48 · Dual specificity protein phosphatase hVH3 · VH3

Resolves to

Protein
UniProtQ16690UniProt nameDUS5_HUMAN
Gene
HGNCHGNC:3071NCBI Gene1847GeneCardsDUSP5
Pharmacology
KEGGhsa:1847
Structure
PDB2G6Z
Drugs

What you can answer from here — as of October 31, 2023

1DrugApproved to experimental, with action, bond type and pharmacological action
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2Clinical trialsTrials of drugs acting on it, by phase and status
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14GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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1+ReferenceStructured and connected to the statements they support
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Which compounds in development act on Dual specificity protein phosphatase 5, and which indications are they being tested in?

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