This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Summary
Merbromin is a topical antiseptic indicated in the disinfection of lacerations.
- Generic Name
- Merbromin
- DrugBank Accession Number
- DB13392
- Background
Mercurochrome is a trade name of merbromin commonly used as a topical first-aid antiseptic agent. It is an organomercuric disodium salt compound and a fluorescein that is available in many countries, except Switzerland, France, Germany, and the United States where the drug was withdrawn from market due to the possibility of mercury poisoning.
- Type
- Small Molecule
- Groups
- Experimental
- Structure
Structure for Merbromin (DB13392)
- Weight
- Average: 750.65
Monoisotopic: 749.818928236 - Chemical Formula
- C20H8Br2HgNa2O6
- Synonyms
- Merbromin
- Merbromina
- Merbromine
- Merbrominum
- Mercurochrome
Pharmacology
- Indication
Not Available
Reduce drug development failure ratesBuild, train, & validate machine-learning modelswith evidence-based and structured datasets.Build, train, & validate predictive machine-learning models with structured datasets.- Associated Therapies
- Contraindications & Blackbox Warnings
Avoid life-threatening adverse drug eventsImprove clinical decision support with information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.Avoid life-threatening adverse drug events & improve clinical decision support.- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates.Improve decision support & research outcomes with our structured adverse effects data.- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Not Available
Products
Drug product information from 10+ global regionsOur datasets provide approved product information including:dosage, form, labeller, route of administration, and marketing period.Access drug product information from over 10 global regions.- International/Other Brands
- Mercurochrome
- Over the Counter Products
Name Dosage Strength Route Labeller Marketing Start Marketing End Region Image ยาน้ำแดง (ซีโต้) ตราเต่าบิน Solution 2 g/100 ml Topical บริษัท ปัจจุบันโอสถ จำกัด จำกัด 1986-02-27 Not applicable Thailand 
ยาแดง Solution 2 g/100 ml Topical ห้างหุ้นส่วนจำกัด โรงงานผลิตยาอันอันโอสถ 1987-05-26 Not applicable Thailand ยาแดง Solution 2 g/100 ml Topical บริษัท วิทยาศรม จำกัด 1985-01-29 Not applicable Thailand ยาแดง - ตราโลโล่ Solution 2 g/100 ml Topical บริษัท แลชแมน จำกัด จำกัด 2001-03-21 Not applicable Thailand ยาแดง (ตรามงกุฏพญานาคคู่) Solution 2 g/100 ml Topical บริษัท ศิริบัญชา จำกัด จำกัด 1987-02-13 2020-08-27 Thailand ยาแดงสหการ Solution 2 g/100 ml Topical บริษัท สหการโอสถ (1996) จำกัด จำกัด 1996-12-26 Not applicable Thailand
Categories
- ATC Codes
- D08AK04 — Merbromin
- Drug Categories
- Chemical TaxonomyProvided by Classyfire
- Description
- This compound belongs to the class of organic compounds known as xanthenes. These are polycyclic aromatic compounds containing a xanthene moiety, which consists of two benzene rings joined to each other by a pyran ring.
- Kingdom
- Organic compounds
- Super Class
- Organoheterocyclic compounds
- Class
- Benzopyrans
- Sub Class
- 1-benzopyrans
- Direct Parent
- Xanthenes
- Alternative Parents
- Benzoic acids and derivatives / Benzoyl derivatives / Metal aryls / Aryl bromides / Heteroaromatic compounds / Cyclic ketones / Carboxylic acid salts / Oxacyclic compounds / Organic transition metal salts / Organic alkali metal salts show 5 more
- Substituents
- Aromatic heteropolycyclic compound / Aryl bromide / Aryl halide / Benzenoid / Benzoic acid or derivatives / Benzoyl / Carboxylic acid derivative / Carboxylic acid salt / Cyclic ketone / Heteroaromatic compound show 18 more
- Molecular Framework
- Aromatic heteropolycyclic compounds
- External Descriptors
- Not Available
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- M0T18YH28D
- CAS number
- 129-16-8
- InChI Key
- SQFDQLBYJKFDDO-UHFFFAOYSA-K
- InChI
- InChI=1S/C20H9Br2O5.Hg.2Na.H2O/c21-13-5-11-17(7-15(13)23)27-18-8-16(24)14(22)6-12(18)19(11)9-3-1-2-4-10(9)20(25)26;;;;/h1-7,24H,(H,25,26);;;;1H2/q;3*+1;/p-3
- IUPAC Name
- disodium [2,7-dibromo-9-(2-carboxylatophenyl)-6-oxido-3-oxo-3H-xanthen-5-yl]mercurol
- SMILES
- [Na+].[Na+].O[Hg]C1=C([O-])C(Br)=CC2=C1OC1=CC(=O)C(Br)=CC1=C2C1=CC=CC=C1C([O-])=O
References
- General References
- FDA Thailand Product Information: Mercurochrome (merbromin) topical solution [Link]
- External Links
Clinical Trials
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
Form Route Strength Solution Topical 2 g Solution Topical Solution Topical 2 g/100 ml - Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source Water Solubility 0.0844 mg/mL ALOGPS logP 3.77 ALOGPS logP 3.07 Chemaxon logS -4 ALOGPS pKa (Strongest Acidic) 3.61 Chemaxon pKa (Strongest Basic) -2 Chemaxon Physiological Charge -2 Chemaxon Hydrogen Acceptor Count 6 Chemaxon Hydrogen Donor Count 1 Chemaxon Polar Surface Area 109.72 Å2 Chemaxon Rotatable Bond Count 2 Chemaxon Refractivity 142.01 m3·mol-1 Chemaxon Polarizability 42.76 Å3 Chemaxon Number of Rings 4 Chemaxon Bioavailability 1 Chemaxon Rule of Five No Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
- Not Available
Drug created at June 23, 2017 20:41 / Updated at June 02, 2021 20:04