Leukocyte surface antigen CD47

BE0010649ProteinHumansCD47

Adhesive protein that mediates cell-to-cell interactions (PubMed:11509594, PubMed:15383453). It is acted on by 17 drugs in DrugBank.

Gene name
CD47
UniProtKB entry
Q08722Swiss-Prot
Cellular location
Cell membrane
Residues / weight
323 residues · 35,213 Da
Also known as
Antigenic surface determinant protein OA3 · IAP · Integrin-associated protein · MER6 · Protein MER6

Resolves to

Protein
UniProtQ08722UniProt nameCD47_HUMAN
Gene
HGNCHGNC:1682NCBI Gene961GeneCardsCD47
Pharmacology
IUPHAR/GtoPdb2943KEGGhsa:961
Structure
PDB2JJSPDB2JJTPDB2VSC
Drugs

What you can answer from here — as of October 31, 2023

17DrugsApproved to experimental, with action, bond type and pharmacological action
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7Clinical trialsTrials of drugs acting on it, by phase and status
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27GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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40+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Leukocyte surface antigen CD47, and which indications are they being tested in?

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