Ontorpacept

DB17116InvestigationalProtein Based Therapies

Ontorpacept: Overview.

Mechanism: Ontorpacept targets and blocks cell surface antigen CD47.
Curator reviewed · 2 references
Also known as: 1-118-signal regulatory protein .alpha. (human) fusion protein with immunoglobulin g1 (human fc fragment), dimer
Code names: PF-07901800 · TTI-621

Resolves to

Compound

Targets

What you can answer from here — as of June 16, 2025

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

4Clinical trialsPhase, status and sponsor resolved per trial

4+ReferencesStructured and connected to the statements they support

Which drugs share a target with Ontorpacept, and which of those have an active Phase 3 trial?

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