Baculoviral IAP repeat-containing protein 7

BE0010707ProteinHumansBIRC7

Apoptotic regulator capable of exerting proapoptotic and anti-apoptotic activities and plays crucial roles in apoptosis, cell proliferation, and cell cycle control (PubMed:11024045, PubMed:11084335, PubMed:11162435, PubMed:16729033, PubMed:17294084). It is acted on by 3 drugs in DrugBank.

Gene name
BIRC7
UniProtKB entry
Q96CA5Swiss-Prot
Cellular location
Nucleus
Residues / weight
298 residues · 32,798 Da
Also known as
2.3.2.27 · KIAP · Kidney inhibitor of apoptosis protein · LIVIN · Melanoma inhibitor of apoptosis protein

Resolves to

Protein
UniProtQ96CA5UniProt nameBIRC7_HUMAN
Gene
HGNCHGNC:13702NCBI Gene79444GeneCardsBIRC7
Pharmacology
IUPHAR/GtoPdb2794KEGGhsa:79444
Structure
PDB1OXNPDB1OXQPDB1OY7
Drugs

What you can answer from here — as of October 31, 2023

3DrugsApproved to experimental, with action, bond type and pharmacological action
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1Clinical trialTrials of drugs acting on it, by phase and status
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20GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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3+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Baculoviral IAP repeat-containing protein 7, and which indications are they being tested in?

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