Xevinapant

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DB16305InvestigationalSmall molecule

Xevinapant: Overview.

Formula / weight: C₃₂H₄₃N₅O₄ · 561.727 g/mol (avg)
Also known as: (5S,8S, 10aR)-N-benzhydryl-5-((S)-2-(methylamino)propanamido)-3-(3-methylbutanoyl)-6-oxodecahydropyrrolo[1,2-a][1,5] diazocine-8-carboxyamide · Iap inhibitor at-406 · PYRROLO(1,2-A)(1,5)DIAZOCINE-8-CARBOXAMIDE, N-(DIPHENYLMETHYL)DECAHYDRO-5-(((2S)-2-(METHYLAMINO)-1-OXOPROPYL)AMINO)-3-(3-METHYL-1-OXOBUTYL)-6-OXO-, (5S,8S,10AR)-
Code names: AT-406 · D-1143 · DEBIO-1143 · SM-406

Resolves to

Compound

UNIIN65WC8PXDDCAS1071992-99-8ChEMBLCHEMBL2158051

Structure

InChIKeyLSXUTRRVVSPWDZ-MKKUMYSQSA-NSMILES[H][C@]12CC[C@H](N1C(=O)[C@H](CN(CC2)C(=O)CC(C)C)NC(=O)[C@H](C)NC)C(=O)NC(C1=CC=CC=C1)C1=CC=CC=C1

Targets

O15392BIRC5Q96CA5BIRC7Q13075NAIPQ13489BIRC3Q13490BIRC2P98170XIAP

What you can answer from here — as of November 05, 2025

6Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

17Clinical trialsPhase, status and sponsor resolved per trial

6+ReferencesStructured and connected to the statements they support

Which drugs share a target with Xevinapant, and which of those have an active Phase 3 trial?

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