Fucose-1-phosphate guanylyltransferase

BE0011155ProteinHumansFPGT

Catalyzes the formation of GDP-L-fucose from GTP and L-fucose-1-phosphate (PubMed:9804772). It is acted on by 1 drug in DrugBank.

Gene name
FPGT
UniProtKB entry
O14772Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
607 residues · 68,009 Da
Also known as
2.7.7.30 · GDP-L-fucose diphosphorylase · GDP-L-fucose pyrophosphorylase · GFPP

Resolves to

Protein
UniProtO14772UniProt nameFPGT_HUMAN
Gene
HGNCHGNC:3825NCBI Gene8790GeneCardsFPGT
Pharmacology
KEGGhsa:8790
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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6GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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3+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Fucose-1-phosphate guanylyltransferase, and which indications are they being tested in?

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