GDP-L-fucose

Star0

DB18689ExperimentalSmall molecule

GDP-L-fucose: Overview.

Mechanism: Pharmacologically active on Alpha-(1,3)-fucosyltransferase 7 and Alpha-(1,6)-fucosyltransferase
Curator reviewed
Formula / weight: C₁₆H₂₅N₅O₁₅P₂ · 589.344 g/mol (avg)
Also known as: Gdp-.beta.-l-fucose · Gdp-fucose · Guanosine 5'-(trihydrogen pyrophosphate), mono(6-deoxy-l-galactopyranosyl) ester · Guanosine 5'-diphospho-.beta.-l-fucose · Guanosine 5'-pyrophosphate, .beta.-l-fucopyranosyl ester

Resolves to

Compound

UNIISM108QK2IHCAS15839-70-0ChEMBLCHEMBL1229250ChEBI13332KEGGC00325

Structure

InChIKeyLQEBEXMHBLQMDB-JGQUBWHWSA-NSMILESC[C@@H]1O[C@H](OP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C2N=C(N)NC3=O)[C@@H](O)[C@H](O)[C@@H]1O

Targets

Q11130FUT7Q9BYC5FUT8

Transporters

Q96A29SLC35C1

What you can answer from here — as of July 19, 2026

2Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

1TransporterSubstrate / inhibitor direction, not just membership

Listed above

26+ReferencesStructured and connected to the statements they support

Which drugs share a target with GDP-L-fucose, and which of those have an active Phase 3 trial?

Answer this in Biopharma OS Sign in to your account

Create a free account or log in to explore the full data card.

Create Account