Krueppel-like factor 4

BE0011713ProteinHumansKLF4

Transcription factor; can act both as activator and as repressor. It is acted on by 1 drug in DrugBank.

Gene name
KLF4
UniProtKB entry
O43474Swiss-Prot
Cellular location
Nucleus
Residues / weight
513 residues · 54,670 Da
Also known as
Epithelial zinc finger protein EZF · EZF · GKLF · Gut-enriched krueppel-like factor

Resolves to

Protein
UniProtO43474UniProt nameKLF4_HUMAN
Gene
HGNCHGNC:6348NCBI Gene9314GeneCardsKLF4
Pharmacology
KEGGhsa:9314
Structure
PDB6VTX
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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54GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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1+ReferenceStructured and connected to the statements they support
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Which compounds in development act on Krueppel-like factor 4, and which indications are they being tested in?

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